3. CSB 2004:
Stanford, CA, USA
3rd International IEEE Computer Society Computational Systems Bioinformatics Conference (CSB 2004), 16-19 August 2004, Stanford, CA, USA.
IEEE Computer Society 2004, ISBN 0-7695-2194-0
Keynote Addresses
- Ron Shamir:
Computational Dissection of Regulatory Networks Using Diverse High-Throughput Data.
2-3

- Eugene W. Myers:
Whole Genome Sequencing, Comparative Genomics, and Systems Biology.
4

Invited Talks
Genomics
- Chang-Heng Chang, Li-Ching Hsieh, Ta-Yuan Chen, Hong-Da Chen, Liaofu Luo, Hoong-Chien Lee:
Shannon Information in Complete Genomes.
20-30

- Hong Liu, Li Li, Asher Zilberstein, Chang S. Hahn:
Segmental Duplications Containing Tandem Repeated Genes Encoding Putative Deubiquitinating Enzymes.
31-39

- Yinhe Cao, Wen-wen Tung, Jianbo Gao:
Recurrence Time Statistics: Versatile Tools for Genomic DNA Sequence Analysis.
40-51

- Vineet Bafna, Shaojie Zhang:
FastR: Fast Database Search Tool for Non-Coding RNA.
52-61

- Lei Chen, Shiyong Lu, Jeffrey L. Ram:
Compressed Pattern Matching in DNA Sequences.
62-68

- Michael Molla, Jude W. Shavlik, Thomas Albert, Todd Richmond, Steven Smith:
A Self-Tuning Method for One-Chip SNP Identification.
69-79

- Pang Ko, Mahesh Narayanan, Anantharaman Kalyanaraman, Srinivas Aluru:
Space-Conserving Optimal DNA-Protein Alignment .
80-88

Evolution and Phylogeny
Transcriptomes
- Stefano Lonardi, Yu Luo:
Gridding and Compression of Microarray Images.
122-130

- Sach Mukherjee, Stephen J. Roberts:
A Theoretical Analysis of Gene Selection.
131-141

- Haifeng Li, Keshu Zhang, Tao Jiang:
Minimum Entropy Clustering and Applications to Gene Expression Analysis.
142-151

- Rui Kuang, Eugene Ie, Ke Wang, Kai Wang, Mahira Siddiqi, Yoav Freund, Christina S. Leslie:
Profile-Based String Kernels for Remote Homology Detection and Motif Extraction.
152-160

- Ryo Yoshida, Tomoyuki Higuchi, Seiya Imoto:
A Mixed Factors Model for Dimension Reduction and Extraction of a Group Structure in Gene Expression Data.
161-172

- Zhaohui Sun, Jingyi Yang, Jitender S. Deogun:
MISAE: A New Approach for Regulatory Motif Extraction.
173-181

- Jinze Liu, Jiong Yang, Wei Wang:
Biclustering in Gene Expression Data by Tendency.
182-193

- Karuturi R. Krishna Murthy, Liu Jian Hua:
Improved Fourier Transform Method for Unsupervised Cell-Cycle Regulated Gene Prediction.
194-203

Proteomics
- Yonghua Han, Bin Ma, Kaizhong Zhang:
SPIDER: Software for Protein Identification from Sequence Tags with De Novo Sequencing Error.
206-215

- Patrik D'haeseleer, George M. Church:
Estimating and Improving Protein Interaction Error Rates.
216-223

- Tolga Can, Orhan Çamoglu, Ambuj K. Singh, Yuan-Fang Wang:
Automated Protein Classification Using Consensus Decision.
224-235

- Bo Yan, Chongle Pan, Victor Olman, Robert L. Hettich, Ying Xu:
Separation of Ion Types in Tandem Mass Spectrometry Data Interpretation - A Graph-Theoretic Approach.
236-244

Structural Bioinformatics
- Zhuozhi Wang, Kaizhong Zhang:
Multiple RNA Structure Alignment.
246-254

- Kreshna Gopal, Tod D. Romo, James C. Sacchettini, Thomas R. Ioerger:
Weighting Features to Recognize 3D Patterns of Electron Density in X-Ray Protein Crystallography.
255-265

- Rahul Singh:
Reasoning about Molecular Similarity and Properties.
266-277

- Christopher James Langmead, Bruce Randall Donald:
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment.
278-289

- Hiroshi Matsui, Kengo Sato, Yasubumi Sakakibara:
Pair Stochastic Tree Adjoining Grammars for Aligning and Predicting Pseudoknot RNA Structures.
290-299

- Shu-Yun Le, Jacob V. Maizel Jr., Kaizhong Zhang:
An Algorithm for Detecting Homologues of Known Structured RNAs in Genomes.
300-310

- Arvind Gupta, Ján Manuch, Ladislav Stacho:
Inverse Protein Folding in 2D HP Mode (Extended Abstract).
311-318

- Lincong Wang, Bruce Randall Donald:
Analysis of a Systematic Search-Based Algorithm for Determining Protein Backbone Structure from a Minimum Number of Residual Dipolar Couplings.
319-330

Pathways & Networks
Applied Bioinformatics
Data Mining & Ontology
- Ying Liu, Brian J. Ciliax, Karin Borges, Venu Dasigi, Ashwin Ram, Shamkant B. Navathe, Ray Dingledine:
Comparison of Two Schemes for Automatic Keyword Extraction from MEDLINE for Functional Gene Clustering.
394-404

- Shiming Dong, Eileen Kraemer:
Calculation, Visualization, and Manipulation of MASTs (Maximum Agreement Subtrees).
405-414

- Raf M. Podowski, John G. Cleary, Nicholas T. Goncharoff, Gregory Amoutzias, William S. Hayes:
AZuRE, a Scalable System for Automated Term Disambiguation of Gene and Protein Names.
415-424

- Sheng Zhong, Lu Tian, Cheng Li, Kai-Florian Storch, Wing Hung Wong:
Comparative Analysis of Gene Sets in the Gene Ontology Space under the Multiple Hypothesis Testing Framework.
425-435

- Jinze Liu, Wei Wang, Jiong Yang:
Gene Ontology Friendly Biclustering of Expression Profiles.
436-447

Biomedical Research
Cellular Multicellular Systems
Comparative Genomics
Data Mining
- Ian Shadforth, Daniel Crowther, Conrad Bessant:
Search-Space Reduction of a Non-Redundant Peptide Database.
470-471

- Samir V. Deshpande, Rabih E. Jabbour, Charles Wick, A. Peter Snyder:
Automated and Rapid Bacterial Identification Using LC-Mass Spectrometry with a Relational Database Management System.
472-473

- John H. Phan, Chang F. Quo, Kejiao Guo, Weimin Feng, Geoffrey Wang, May D. Wang:
Development of a Knowledge-Based Multi-Scheme Cancer Microarray Data Analysis System.
474-475

- Fang Liu, Tor-Kristian Jenssen, Vegard Nygaard, John Sack, Eivind Hovig:
FigSearch: Using Maximum Entropy Classifier to Categorize Biological Figures.
476-477

- Maxim Shklar, Orit Shmueli, Liora Strichman-Almashanu, Michael Shmoish, Doron Lancet, Marilyn Safran:
GeneTide: Terra Incognita Discovery Endeavor Mining ESTs and Expression Data to Elucidate Known and De-Novo GeneCards Genes.
478-479

- Mehmet Koyutürk, Wojciech Szpankowski, Ananth Grama:
Biclustering Gene-Feature Matrices for Statistically Significant Dense Patterns.
480-484

- Xuanfu Wu, Zhengxin Chen:
Recognition of Exon/Intron Boundaries Using Dynamic Ensembles.
485-486

- Sach Mukherjee, Stephen J. Roberts:
Probabilistic Consistency Analysis for Gene Selection.
487-488

- Zoé Lacroix, Kaushal Parekh, Hasan Davulcu, I. V. Ramakrishnan, Nikeeta Julasana:
Automating the Biological Data Collection Process with Agents.
489-490

- Jeffrey Stone, Xindong Wu, Marc Greenblatt:
An Intelligent Digital Library System for Biologists.
491-492

- Huimin Geng, Dhundy Bastola, Hesham H. Ali:
A New Approach to Clustering Biological Data Using Message Passing.
493-494

- Daniel Quest, Hesham H. Ali:
Ontology Specific Data Mining Based on Dynamic Grammars.
495-496

- Yuhang Wang, Fillia Makedon:
Application of Relief-F Feature Filtering Algorithm to Selecting Informative Genes for Cancer Classification Using Microarray Data.
497-498

- Andrey Gorin, Robert M. Day, Andrey Borziak, Michael B. Strader, Gregory B. Hurst, Tema Fridman:
Probability Profile Method -- New Approach to Data Analysis in Tandem Mass Spectrometry.
499-502

- Tomonori Izumitani, Hirotoshi Taira, Hideto Kazawa, Eisaku Maeda:
Assigning Gene Ontology Categories (GO) to Yeast Genes Using Text-Based Supervised Learning Methods.
503-504

- Robert M. Day, Andrey Borziak, Andrey Gorin:
PPM-Chain De novo Peptide Identification Program Comparable in Performance to Sequest.
505-508

Evolution and Phylogenetics
- Zhenhua Guo, John W. Stiller:
Comparative Genomics of Cyclin-Dependent Kinases Suggest Co-Evolution of the RNAP II C-Terminal Domain and CTD-Directed CDKs.
510-511

- Terrence S. T. Mak, Kai-Pui Lam:
Embedded Computation of Maximum-Likelihood Phylogeny Inference Using Platform FPGA.
512-514

- Boris Budagyan, Ann E. Loraine:
Gene Length and Alternative Transcription in Fruit Fly.
515-516

- Francisca Zanoguera, Massimo de Francesco:
Protein Classification into Domains of Life Using Markov Chain Models.
517-519

- Weihong Qi, David W. Lacher, Alyssa C. Bumbaugh, Katie E. Hyma, Lindsey M. Ouellette, Teresa M. Large, Cheryl L. Tarr, Thomas S. Whittam:
EcMLST: An Online Database for Multi Locus Sequence Typing of Pathogenic Escherichia coli.
520-521

- Fei Nan, Donald A. Adjeroh:
On Complexity Measures for Biological Sequences.
522-526

Functional Genomics
- Allison Griggs, Shuba Gopal:
A Markov Model Based Gene Discrimination Approach in Trypanosomes.
528

- Jonathan J. Ward, Jaspreet Singh Sodhi, Bernard F. Buxton, David T. Jones:
Predicting Gene Ontology Annotations from Sequence Data Using Kernel-Based Machine Learning Algorithms.
529-530

- Yan Qi, Jianbo Gao, Yinhe Cao, Wen-wen Tung:
Deriving a Novel Codon Index by Combining Period-3 and Fractal Features of DNA Sequences.
531-532

- Kirt M. Noël, Kay C. Wiese:
Exploring the Use of Stem-Loop Characteristics for Pinpointing Structural RNA Genes.
533-534

- Richard F. Meraz, Xiaofeng He, Chris H. Q. Ding, Stephen R. Holbrook:
Positive Sample Only Learning (PSOL) for Predicting RNA Genes in E. coli.
535-538

High Content Analysis
High Performance Computing
Microarray Analysis
- Xiao Yang:
Qvalue Method May Not Always Control False Discovery Rate in Genomics Applications.
556-557

- Dongqing Liu, Ting Shi, Joseph A. DiDonato, John D. Carpten, Jianping Zhu, Zhong-Hui Duan:
Application of a Genetic Algorithm/K-Nearest Neighbor Method to the Classification of Renal Cell Carcinoma.
558-559

- Haili Jiao, Peixin Yang, Zhengxin Chen:
Mining Estrogen Microarray Data: An Approach Using Contrast Data Analysis.
560-561

- Weimin Feng, Gaurav Tuteja, May D. Wang:
EGOMinor: A Genomics and Proteomics Data Computation and Interpretation System for Biomedical Applications.
562-563

- Bill Martin, Robert M. Horton:
A Java Program to Create Simulated Microarray Images.
564-565

- Shawn Martin, George Davidson, Elebeoba E. May, Jean-Loup Faulon, Margaret Werner-Washburne:
Inferring Genetic Networks from Microarray Data.
566-569

- Nini Rao, Simon J. Shepherd:
Extracting Characteristic Patterns from Genome - Wide Expression Data by Non-Negative Matrix Factorization.
570-571

- Hyunsoo Kim, Gene H. Golub, Haesun Park:
Imputation of Missing Values in DNA Microarray Gene Expression Data.
572-573

- Qian Diao, Wei Hu, Hao Zhong, Juntao Li, Feng Xue, Tao Wang, Yimin Zhang:
Disease Gene Explorer: Display Disease Gene Dependency by Combining Bayesian Networks with Clustering.
574-575

- Yuan-Kai Wang, Cheng-Wei Huang:
DNA Microarray Image Analysis Using Active Contour Model.
576-577

- Danny Barash, Dorin Comaniciu:
Meanshift Clustering for DNA Microarray Analysis.
578-579

- Yizhou Xie, Soumitra Ghosh, Parthav Jailwalia, Xujing Wang:
The Dynamic Range of Gene Expressions Depend on Their Ontology.
580-581

- Hui Fang, ChengXiang Zhai, Lei Liu, Jiong Yang:
Subspace Clustering for Microarray Data Analysis: Multiple Criteria and Significance Assessment.
582-583

- John A. Berger, Sampsa Hautaniemi, Sanjit K. Mitra:
Comparative Analysis of Gene Expression and DNA Copy Number Data for Pancreatic and Breast Cancers Using an Orthogonal Decomposition.
584-585

- Geoffrey Yang, Ming-Hsiu Ho, Earl Hubbell:
High-Throughput Microarray-Based Genotyping.
586-587

Other
- Lawrence D'Antonio, Paramjeet Singh Bagga:
Computational Methods for Predicting Intramolecular G-Quadruplexes in Nucleotide Sequences.
590-591

- Xiequn Xu, W. Bradley Barbazuk, Yucheng Feng, Karel Schubert, Agnes P. Chan, Geo Pertea, Li Zheng, Foo Cheung, Yuandan Lee:
Gene Recovery of Two Genome-Filtration Sequencing Techniques When Applied to the Maize Genome.
594-595

- Zoé Lacroix, Kaushal Parekh, Louiqa Raschid, Maria-Esther Vidal:
Navigating through the Biological Maze.
594-595

- Zoé Lacroix, Vidyadhari Edupuganti:
How Biological Source Capabilities May Affect the Data Collection Process.
596-597

- Stephan Heymann, Felix Naumann, Louiqa Raschid, Peter Rieger:
Labeling and Enhancing Life Sciences Links.
598-599

Pathways Networks Systems Biology
- Alireza Darvish, EunSang Bak, Krishna Gopalakrishnan, R. H. Zadeh, Kayvan Najarian:
A New Hierarchical Method for Identification of Dynamic Regulatory Pathways from Time-Series DNA Microarray Data.
602-603

- Pei Wang, Young Kim, Jonathan R. Pollack, Robert Tibshirani:
Boosted PRIM with Application to Searching for Oncogenic Pathway of Lung Cancer.
604-609

- Fang-Xiang Wu, Anthony J. Kusalik, Wen-Jun Zhang:
A. Genetic Algorithm for Inferring Time Delays in Gene Regulatory Networks.
610-611

- Peng Wang, Zhengchang Su, PhuongAn Dam, Ying Xu:
A Knowledge Base for Computational Pathway Reconstruction.
612-613

- PhuongAn Dam, Zhengchang Su, Victor Olman, Ying Xu:
In Silico Construction of the Carbon Fixation Pathway in Synechococcus sp. WH8102.
614-615

- Stephen A. Racunas, Christopher Griffin, Nigam Shah:
A Finite Model Theory for Biological Hypotheses.
616-620

- Hee Young Kang, Hak Yong Kim:
Functional Modules from Protein Networks of Kinome and Cell Cycle in Saccharomyces Cerevisiae.
621-622

- Olusola C. Idowu, Steven J. Lynden, Malcolm P. Young, Péter András:
Bacillus Subtilis Protein Interaction Network Analysis.
623-625

- Jean-Loup Faulon, Shawn Martin, Robert D. Carr:
Dynamical Robustness in Gene Regulatory Networks.
626-627

- Catalin C. Barbacioru, Daniel J. Cowden, Joel H. Saltz:
An Algorithm for Reconstruction of Markov Blankets in Bayesian Networks of Gene Expression Datasets.
628-629

- Jianbo Gao, Jesse S. A. Bridgewater, Vwani P. Roychowdhury:
Synchronized Oscillations and Chaos in Coupled Genetic Repressilators.
630-631

- Kohei Taki, Reiji Teramoto, Yoichi Takenaka, Hideo Matsuda:
Inference of Gene Regulatory Network Based on Module Network Model with Gene Functional Classifications.
632-633

- Shoko Miyake, Yoichi Takenaka, Hideo Matsuda:
A Graph Analysis Method to Detect Metabolic Sub-Networks Based on Phylogenetic Profile.
634-635

- Lie-Quan Lee, Jeff Varner, Kwok Ko:
Parallel Extreme Pathway Computation for Metabolic Networks.
636-639

- Zhengchang Su, PhuongAn Dam, X. Chen, Victor Olman, Tao Jiang, Ying Xu:
Computational Construction of Nitrogen Assimilation Pathway in Cyanobacteria Synechococcus sp. WH8102.
640-641

- Fenglou Mao, Zhengchang Su, Victor Olman, David Chuang, Ying Xu:
Pathway Mapping with Operon Information: An Integer-Programming Method.
642-643

- Karen Sachs, Omar D. Perez, Dana Pe'er, Garry P. Nolan, David K. Gifford, Tommi Jaakkola, Douglas A. Lauffenburger:
Analysis of Signaling Pathways in Human T-Cells Using Bayesian Network Modeling of Single Cell Data.
644

- Wei Wang, Gregory F. Cooper:
An Bayesian Method for Biological Pathway Discovery from High-Throughput Experimental Data.
645-646

- Tie Wang, Jeffrey W. Touchman, Guoliang Xue:
Applying Two-Level Simulated Annealing on Bayesian Structure Learning to Infer Genetic Networks.
647-648

Pattern Recognition
- Hsiao Ping Lee, Tzu Fang Sheu, Yin-Te Tsai, Ching Hua Shih, Chuan Yi Tang:
A Efficient Algorithm for Unique Signature Discovery on Whole-Genome EST Databases.
650-651

- Yan Ding, Hong Cao, Shu Wen:
VirusFinder: A Web-Based Virus Identification System Using Viral Nucleotide Signatures.
652-653

- Jian Liu, Ming Li:
Finding Cancer Biomarkers from Mass Spectrometry Data by Decision Lists.
654-655

- Hyunsoo Kim, Haesun Park:
Incremental and Decremental Least Squares Support Vector Machine and Its Application to Drug Design.
656-657

- Eugene Lin, Dennis Chen, Yuchi Hwang, Ashely Chang, Z. John Gu:
A Prediction Model for the Drug Efficacy of Interferon in CHC Patients Based on SNPs.
658-659

- Oriel Bergig, Danny Barash, Klara Kedem:
RNA Motif Search Using the Structure to String (STR2) Method.
660-661

- Ravi Vijaya Satya, Amar Mukherjee:
PRUNER: Algorithms for Finding Monad Patterns in DNA Sequences.
662-665

- Victor Olman, Jizhu Lu, PhuongAn Dam, Zhengchang Su, Ying Xu:
CUBIC: Search for Binding Sites.
666-667

- Kevin Crosby, Paula Gabbert:
BioSPRINT: Classification of Intron and Exon Sequences Using the SPRINT Algorithm.
668-669

- Xutao Deng, Hesham H. Ali:
A Hidden Markov Model for Gene Function Prediction from Sequential Expression Data.
670-671

- Alexandre Tchourbanov, Hesham H. Ali, Jitender S. Deogun:
Using Enhancing Signals to Improve Specificity of ab initio Splice Site Sensors.
672-673

- Xiaolu Huang, Hesham H. Ali, Anguraj Sadanandam, Rakesh K. Singh:
SRPVS: A New Motif Searching Algorithm for Protein Analysis.
674-675

- Donald A. Adjeroh, Jianan Feng:
Locating All Tandem Repeat Families in a Sequence.
676-681

Promoter Analysis
Protein Structure Analysis
- Krishna Gopalakrishnan, R. H. Zadeh, Kayvan Najarian, Alireza Darvish:
Computational Analysis and Classification of p53 Mutants According to Primary Structure.
694-695

- Gong-Xin Yu, Byung-Hoon Park, Praveen Chandramohan, Al Geist, Nagiza F. Samatova:
In-Silico Prediction of Surface Residue Clusters for Enzyme-Substrate Specificity.
696-697

- Chenyang Cui, Donghui Wang, Jiaoying Shi:
Comparing 3D Protein Structures Similarity by Using Fractal Features.
698-699

- Peng Wang, Zhengchang Su, Jun-tao Guo, Ying Xu:
Structural Analysis of FGFR1 Kinase Activation through Molecular Dynamics Simulation.
700-701

- Jaspreet Singh Sodhi, Liam J. McGuffin, Kevin Bryson, Jonathan J. Ward, Lorenz Wernisch, David T. Jones:
Automatic Prediction of Functional Site Regions in Low-Resolution Protein Structures.
702-703

- Barrett Abel, Martin Gollery:
BPAP: A Computational Tool for Whole Genome Analysis and Annotation.
704-705

- Todd J. Taylor, Iosif I. Vaisman:
A New Method of Secondary Structure Assignment Based on the Delaunay Tessellation of Protein Structures.
706-707

- Jun-tao Guo, Ying Xu:
Molecular Modeling of Full-Length OxyR from Shewanella oneidensis MR-1 and Molecular Dynamics Studies of the Activation Domain.
708-709

- Sumeet Dua, Naveen Kandiraju:
A Novel Computational Framework for Structural Classification of Proteins Using Local Geometric Parameter Matching.
710-711

- K. Arun, Christopher James Langmead:
Large-Scale Testing of Chemical Shift Prediction Algorithms and Improved Machine Learning-Based Approaches to Shift Prediction.
712-713

RNAi Analysis
Sequence Alignment
SNPs and Haplotyping
Synthetic Biological Systems
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