Volume 12, Number 1, January 2011
Papers
- Carol Wong, Yuran Li, Chih Lee, Chun-Hsi Huang:
Ensemble learning algorithms for classification of mtDNA into haplogroups.
1-9

- Mark A. van de Wiel, Franck Picard, Wessel N. van Wieringen, Bauke Ylstra:
Preprocessing and downstream analysis of microarray DNA copy number profiles.
10-21

- Léon-Charles Tranchevent, Francisco Bonachela Capdevila, Daniela Nitsch, Bart De Moor, Patrick De Causmaecker, Yves Moreau:
A guide to web tools to prioritize candidate genes.
22-32

- Shuangge Ma, Xiao Song:
Ranking prognosis markers in cancer genomic studies.
33-40

- Melissa J. Hubisz, Katherine S. Pollard, Adam C. Siepel:
PHAST and RPHAST: phylogenetic analysis with space/time models.
41-51

- Emanuela Gadaleta, Nicholas R. Lemoine, Claude Chelala:
Online resources of cancer data: barriers, benefits and lessons.
52-63

- Francisco Azuaje:
Computational discrete models of tissue growth and regeneration.
64-77

Book Reviews
- Medha Bhagwat, Lynn Young:
Bioinformatics.Charlie Hodgman, Andrew French and David Westhead Instant.
78-79

- Xiang Zhang:
Proteome Bioinformatics. Edited by Simon J. Hubbard and Andrew R. Jones, .
80-81

- Seonho Kim:
Knowledge-Based Bioinformatics - From analysis to interpretation.Edited by Gil Alterovitz and Marco Ramoni.
82-85

Letter to the Editor
Volume 12, Number 2, March 2011
- Anália Lourenço, Sónia Carneiro, Miguel Rocha, Eugénio C. Ferreira, Isabel Rocha:
Challenges in integrating Escherichia coli molecular biology data.
91-103

- Danny Barash, Alexander Churkin:
Mutational analysis in RNAs: comparing programs for RNA deleterious mutation prediction.
104-114

- Xinbin Dai, Zhaohong Zhuang, Patrick Xuechun Zhao:
Computational analysis of miRNA targets in plants: current status and challenges.
115-121

- Georg Fuellen:
Evolution of gene regulation - on the road towards computational inferences.
122-131

- Yanping Xi, Yi-Ping Phoebe Chen, Chen Qian, Fei Wang:
Comparative study of computational methods to detect the correlated reaction sets in biochemical networks.
132-150

- Andrés Pinzón, Luis M. Rodriguez-R, Andrés González, Adriana Bernal, Silvia Restrepo:
Targeted metabolic reconstruction: a novel approach for the characterization of plant-pathogen interactions.
151-162

- Singaravelu Kalaimathy, Ramanathan Sowdhamini, Karuppiah Kanagarajadurai:
Critical assessment of structure-based sequence alignment methods at distant relationships.
163-175

- Pascal Roy, Caroline Truntzer, Delphine Maucort-Boulch, Thomas Jouve, Nicolas Molinari:
Protein mass spectra data analysis for clinical biomarker discovery: a global review.
176-186

Volume 12, Number 3, May 2011
Editorial
Special Issue Papers
- Peter J. Castaldi, Issa J. Dahabreh, John P. A. Ioannidis:
An empirical assessment of validation practices for molecular classifiers.
189-202

- Richard M. Simon, Jyothi Subramanian, Ming-Chung Li, Supriya Menezes:
Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data.
203-214

- Anne-Laure Boulesteix, Willi Sauerbrei:
Added predictive value of high-throughput molecular data to clinical data and its validation.
215-229

- Ulrich Mansmann, Vindi Jurinovic:
Biological feature validation of estimated gene interaction networks from microarray data: a case study on MYC in lymphomas.
230-244

- Edward R. Dougherty:
Validation of gene regulatory networks: scientific and inferential.
245-252

- Inke R. König:
Validation in Genetic Association Studies.
253-258

- John R. Thompson, John Attia, Cosetta Minelli:
The meta-analysis of genome-wide association studies.
259-269

- Alexandros Stamatakis, Fernando Izquierdo-Carrasco:
Result verification, code verification and computation of support values in phylogenetics.
270-279

- Zhide Fang, Xiangqin Cui:
Design and validation issues in RNA-seq experiments.
280-287

- Torsten Hothorn, Friedrich Leisch:
Case studies in reproducibility.
288-300

Volume 12, Number 4, July 2011
- Philippe Sanseau, Jacob Koehler:
Editorial: Computational methods for drug repurposing.
301-302

- Joel Dudley, Tarangini Deshpande, Atul J. Butte:
Exploiting drug-disease relationships for computational drug repositioning.
303-311

- V. Joachim Haupt, Michael Schroeder:
Old friends in new guise: repositioning of known drugs with structural bioinformatics.
312-326

- Sanjay Joshua Swamidass:
Mining small-molecule screens to repurpose drugs.
327-335

- Fabrice Moriaud, Stéphane B. Richard, Stewart A. Adcock, Laetitia Chanas-Martin, Jean-Sébastien Surgand, Marouane Ben Jelloul, François Delfaud:
Identify drug repurposing candidates by mining the Protein Data Bank.
336-340

- Kui Xu, Timothy R. Coté:
Database identifies FDA-approved drugs with potential to be repurposed for treatment of orphan diseases.
341-345

- Divya Sardana, Cheng Zhu, Minlu Zhang, Ranga Chandra Gudivada, Lun Yang, Anil G. Jegga:
Drug repositioning for orphan diseases.
346-356

- Christos Andronis, Anuj Sharma, Vassilis Virvilis, Spyros Deftereos, Aris Persidis:
Literature mining, ontologies and information visualization for drug repurposing.
357-368

- Kristin K. Nicodemus:
Letter to the Editor: On the stability and ranking of predictors from random forest variable importance measures.
369-373

Volume 12, Number 5, September 2011
Editorial
Obituary
Special Issue Papers
- David M. Kristensen, Yuri I. Wolf, Arcady R. Mushegian, Eugene V. Koonin:
Computational methods for Gene Orthology inference.
379-391

- Jean-Philippe Doyon, Vincent Ranwez, Vincent Daubin, Vincent Berry:
Models, algorithms and programs for phylogeny reconciliation.
392-400

- Colin N. Dewey:
Positional orthology: putting genomic evolutionary relationships into context.
401-412

- Kimmen Sjölander, Ruchira S. Datta, Yaoqing Shen, Grant M. Shoffner:
Ortholog identification in the presence of domain architecture rearrangement.
413-422

- Brigitte Boeckmann, Marc Robinson-Rechavi, Ioannis Xenarios, Christophe Dessimoz:
Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees.
423-435

- Walid H. Gharib, Marc Robinson-Rechavi:
When orthologs diverge between human and mouse.
436-441

- Jaime Huerta-Cepas, Joaquín Dopazo, Martijn A. Huynen, Toni Gabaldón:
Evidence for short-time divergence and long-time conservation of tissue-specific expression after gene duplication.
442-448

- Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas:
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
449-462

- Kristoffer Forslund, Fabian Schreiber, Nattaphon Thanintorn, Erik L. L. Sonnhammer:
OrthoDisease: tracking disease gene orthologs across 100 species.
463-473

- Christophe Dessimoz, Stefan Zoller, Tereza Manousaki, Huan Qiu, Axel Meyer, Shigehiro Kuraku:
Comparative genomics approach to detecting split-coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes).
474-484

Letter to the Editor
Non Special Issue Papers
- Christian Ledergerber, Christophe Dessimoz:
Base-calling for next-generation sequencing platforms.
489-497

- Alan Wee-Chung Liew, Ngai-Fong Law, Hong Yan:
Missing value imputation for gene expression data: computational techniques to recover missing data from available information.
498-513

- Nicolas von Ahsen, Carl T. Wittwer, Ekkehard Schütz:
Monovalent and divalent salt correction algorithms for Tm prediction - recommendations for Primer3 usage.
514-517

- Rob Jelier, Jelle J. Goeman, Kristina M. Hettne, Martijn J. Schuemie, Johan T. den Dunnen, Peter A. C. 't Hoen:
Literature-aided interpretation of gene expression data with the weighted global test.
518-529

- Yves Sucaet, Taru Deva:
Evolution and applications of plant pathway resources and databases.
530-544

Letter to the Editor
- Adam Wittek, Karol Miller:
Letter to the Editor: Current progress in patient-specific modeling by Neal and Kerckhoffs (2010).
545-546

Volume 12, Number 6, November 2011
Editorial
Special Issue Papers
- Paolo Romano, Rosalba Giugno, Alfredo Pulvirenti:
Tools and collaborative environments for bioinformatics research.
549-561

- Andrea Splendiani, Michaela Gündel, Jonathan M. Austyn, Duccio Cavalieri, Ciro Scognamiglio, Marco Brandizi:
Knowledge sharing and collaboration in translational research, and the DC-THERA Directory.
562-575

- Ismael Navas Delgado, Alejandro Real-Chicharro, Miguel Angel Medina, Francisca Sánchez-Jiménez, José Francisco Aldana Montes:
Social pathway annotation: extensions of the systems biology metabolic modelling assistant.
576-587

- Dario Corrada, Federica Viti, Ivan Merelli, Cristina Battaglia, Luciano Milanesi:
myMIR: a genome-wide microRNA targets identification and annotation tool.
588-600

- Magdalena Rother, Kristian Rother, Tomasz Puton, Janusz M. Bujnicki:
RNA tertiary structure prediction with ModeRNA.
601-613

- Paolo Ribeca, Gabriel Valiente:
Computational challenges of sequence classification in microbiomic data.
614-625

Non Special Issue Papers
- Adam M. Szalkowski, Christoph D. Schmid:
Rapid innovation in ChIP-seq peak-calling algorithms is outdistancing benchmarking efforts.
626-633

- Helen E. Lockstone:
Exon array data analysis using Affymetrix power tools and R statistical software.
634-644

- Yijun Meng, Chaogang Shao, Ming Chen:
Toward microRNA-mediated gene regulatory networks in plants.
645-659

- Shannon L. N. Mayne, Hugh-George Patterton:
Bioinformatics tools for the structural elucidation of multi-subunit protein complexes by mass spectrometric analysis of protein-protein cross-links.
660-671

- Hua Zhang, Tuo Zhang, Ke Chen, Kanaka Durga Kedarisetti, Marcin J. Mizianty, Qingbo Bao, Wojciech Stach, Lukasz A. Kurgan:
Critical assessment of high-throughput standalone methods for secondary structure prediction.
672-688

- Matthieu Chavent, Bruno Lévy, Michael Krone, Katrin Bidmon, Jean-Philippe Nomine, Thomas Ertl, Marc Baaden:
GPU-powered tools boost molecular visualization.
689-701

- Tomas Klingström, Dariusz Plewczynski:
Protein-protein interaction and pathway databases, a graphical review.
702-713

- Shuangge Ma, Ying Dai:
Principal component analysis based methods in bioinformatics studies.
714-722

- Louis du Plessis, Nives Skunca, Christophe Dessimoz:
The what, where, how and why of gene ontology - a primer for bioinformaticians.
723-735

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