Volume 14, Number 1, February 1998
Articles
- Barbara A. Eckman, Jeffery S. Aaronson, J. A. Borkowski, W. J. Bailey, K. O. Elliston, A. R. Williamson, R. A. Blevins:
The Merck Gene Index browser: an extensible data integration system for gene finding, gene characterization and EST data mining.
2-13

- Sing-Hoi Sze, Mikhail A. Roytberg, Mikhail S. Gelfand, Andrey A. Mironov, Tatiana V. Astakhova, Pavel A. Pevzner:
Algorithms and software for support of gene identification experiments.
14-19

- Frédéric Achard, Philippe Dessen:
GenXref. VI: Automatic generation of links between two heterogeneous databases.
20-24

- Jun Zhu, Jun S. Liu, Charles E. Lawrence:
Bayesian adaptive sequence alignment algorithms.
25-39

- Pankaj Agarwal, David J. States:
Comparative accuracy of methods for protein sequence similarity search.
40-47

- Timothy L. Bailey, Michael Gribskov:
Combining evidence using p-values: application to sequence homology searches.
48-54

- Isidore Rigoutsos, Aris Floratos:
Combinatorial pattern discovery in biological sequences: The TEIRESIAS algorithm [published erratum appears in Bioinformatics 1998;14(2): 229].
55-67

- Daniel H. Huson:
SplitsTree: analyzing and visualizing evolutionary data.
68-73

- Samuel Levy, L. Compagnoni, Eugene W. Myers, Gary D. Stormo:
Xlandscape: the graphical display of word frequencies in sequences.
74-80

- Karsten R. Heidtke, Steffen Schulze-Kremer:
Design and implementation of a qualitative simulation model of lambda phage infection.
81-91

- Richard Mott:
Trace alignment and some of its applications.
92-97

- Michael A. Charleston:
Spectrum: spectral analysis of phylogenetic data.
98-99

Volume 14, Number 2, March 1998
Articles
- J. A. Inglehart, P. C. Nelson, Y. Zou:
Mapper: an intelligent restriction mapping tool.
101-111

- Jian Hu, Chris Mungall, David Nicholson, Alan L. Archibald:
Design and implementation of a CORBA-based genome mapping system prototype.
112-120

- Vladimir Brusic, George B. Rudy, G. Honeyman, Jürgen Hammer, Leonard C. Harrison:
Prediction of MHC class II-binding peptides using an evolutionary algorithm and artificial neural network.
121-130

- Rupali V. Parbhane, Sanjeev S. Tambe, Bhaskar D. Kulkarni:
Analysis of DNA curvature using artificial neural networks.
131-138

- Nadia A. Chuzhanova, Antonia J. Jones, Steve Margetts:
Feature selection for genetic sequence classification.
139-143

- Jong Park, Sarah A. Teichmann:
DIVCLUS: an automatic method in the GEANFAMMER package that finds homologous domains in single- and multi-domain proteins.
144-150

- D. K. Smith, H. Xue:
A major component approach to presenting consensus sequences.
151-156

- Jens Stoye, Dirk Evers, Folker Meyer:
Rose: generating sequence families.
157-163

- Jérôme Gracy, P. Argos:
Automated protein sequence database classification. I. Integration of compositional similarity search, local similarity search, and multiple sequence alignment.
164-173

- Jérôme Gracy, P. Argos:
Automated protein sequence database classification. II. Delineation Of domain boundaries from sequence similarities.
174-187

- Jianghong An, T. Nakama, Y. Kubota, Akinori Sarai:
3DinSight: an integrated relational database and search tool for the structure, function and properties of biomolecules.
188-195

- Friedrich Ackermann, Grit Herrmann, Stefan Posch, Gerhard Sagerer:
Estimation and filtering of potential protein-protein docking positions.
196-205

- Gilles Labesse, J. P. Mornon:
Incremental threading optimization (TITO) to help alignment and modelling of remote homologues.
206-211

- Salvatore Lanzavecchia, Pier Luigi Bellon:
Fast computation of 3D radon transform via a direct Fourier method.
212-216

- S. Taylor, T. Charles Hodgman, C. B. Littler, Roger A. Sayle, R. W. Gill, M. D. Oxer, C. H. O'Donnell, Andrew Lyall:
Automated management of gene discovery projects.
217-218

- Gráinne McGuire, Frank Wright:
TOPAL: recombination detection in DNA and protein sequences.
219-220

- Giovanni Iazzetti, M. L. Chiusano, Raffaele Calogero:
STRIRED: graphical analysis of string repeats.
221-222

- Cathy H. Wu, Sailaja Shivakumar, Chittari V. Shivakumar, Sheng-Chih Chen:
GeneFIND web server for protein family identification and information retrieval.
223-224

- B. V. B. Reddy, P. Ramesh, S. Tiwari:
MEICPS: substitution mutations to engineer intracellular protein stability.
225-226

- A. Hernandez, M. T. Ruiz:
An EXCEL template for calculation of enzyme kinetic parameters by non-linear regression.
227-228

Volume 14, Number 3, April 1998
Articles
- Jürgen Kleffe, Klaus Hermann, W. Vahrson, Burghardt Wittig, Volker Brendel:
GeneGenerator - a flexible algorithm for gene prediction and its application to maize sequences.
232-243

- L. Pickert, Ingmar Reuter, Frank Klawonn, Edgar Wingender:
Transcription regulatory region analysis using signal detection and fuzzy clustering.
244-251

- Andrei Grigoriev, Alexander Levin, Hans Lehrach:
A distributed environment for physical map construction.
252-258

- Alexander E. Kel, Andrey A. Ptitsyn, Vladimir N. Babenko, Sebastian Meier-Ewert, Hans Lehrach:
A genetic algorithm for designing gene family-specific oligonucleotide sets used for hybridization: the G protein-coupled receptor protein superfamily.
259-270

- Thomas Dandekar, Katrin Beyer, Peer Bork, Mary-Rose Kenealy, Kostas Pantopoulos, Matthias W. Hentze, Vera Sonntag-Buck, Gilles Flouriot, Frank Gannon, Sonja Schreiber:
Systematic genomic screening and analysis of mRNA in untranslated regions and mRNA precursors: combining experimental and computational approaches.
271-278

- Rainer Spang, Martin Vingron:
Statistics of large-scale sequence searching.
279-284

- Yan P. Yuan, Oliver Eulenstein, Martin Vingron, Peer Bork:
Towards detection of orthologues in sequence databases.
285-289

- Burkhard Morgenstern, Kornelie Frech, Andreas W. M. Dress, Thomas Werner:
DIALIGN: finding local similarities by multiple sequence alignment.
290-294

- Ralf Zimmer, Marko Wöhler, Ralf Thiele:
New scoring schemes for protein fold recognition based on Voronoi contacts.
295-308

Volume 14, Number 4, May 1998
Articles
- Prakash M. Nadkarni:
Mapmerge: merge genomic maps.
310-316

- Tetsushi Yada, Yasushi Totoki, Masato Ishikawa, Kiyoshi Asai, Kenta Nakai:
Automatic extraction of motifs represented in the hidden Markov model from a number of DNA sequences.
317-325

- M. Dlakic, R. E. Harrington:
DIAMOD: display and modeling of DNA bending.
326-331

- Emmet A. O'Brien, Cédric Notredame, Desmond G. Higgins:
Optimization of ribosomal RNA profile alignments.
332-341

- Frédéric Achard, Christophe Cussat-Blanc, Eric Viara, Emmanuel Barillot:
The new Virgil database: a service of rich links.
342-348

- I. Anderson, A. Brass:
Searching DNA databases for similarities to DNA sequences: when is a match significant?
349-356

- P. Briffeuil, G. Baudoux, Christophe G. Lambert, Xavier De Bolle, C. Vinals, Ernest Feytmans, Eric Depiereux:
Comparative analysis of seven multiple protein sequence alignment servers: clues to enhance reliability of predictions.
357-366

- N. P. Brown, Chris Sander, Peer Bork:
Frame: detection of genomic sequencing errors.
367-371

- James O. McInerney:
GCUA: general codon usage analysis.
372-373

- S. Levin, B. H. Satir:
POLINA: detection and evaluation of single amino acid substitutions in protein superfamilies.
374-375

- Huaichun Wang, Joaquín Dopazo, José María Carazo:
Self-organizing tree growing network for classifying amino acids.
376-377

- Takatsugu Hirokawa, S. Boon-Chieng, Shigeki Mitaku:
SOSUI: classification and secondary structure prediction system for membrane proteins.
378-379

- N. P. Brown, Christophe Leroy, Chris Sander:
MView: a web-compatible database search or multiple alignment viewer.
380-381

Volume 14, Number 5, June 1998
Articles
- Asaf A. Salamov, Tetsuo Nishikawa, Mark B. Swindells:
Assessing protein coding region integrity in cDNA sequencing projects.
384-390

- Denis Thieffry, Heladia Salgado, Araceli M. Huerta, Julio Collado-Vides:
Prediction of transcriptional regulatory sites in the complete genome sequence of Escherichia coli K-12.
391-400

- C. Tarnas, Richard Hughey:
Reduced space hidden Markov model training.
401-406

- Cédric Notredame, Liisa Holm, Desmond G. Higgins:
COFFEE: an objective function for multiple sequence alignments.
407-422

- Liisa Holm, Chris Sander:
Removing near-neighbour redundancy from large protein sequence collections.
423-429

- Antje Krause, Martin Vingron:
A set-theoretic approach to database searching and clustering.
430-438

- Oswaldo Trelles, Miguel A. Andrade, Alfonso Valencia, Emilio L. Zapata, José María Carazo:
Computational space reduction and parallelization of a new clustering approach for large groups of sequences.
439-451

- Martin Senger, T. Flores, Karl-Heinz Glatting, Peter Ernst, Agnes Hotz-Wagenblatt, Sándor Suhai:
W2H: WWW interface to the GCG sequence analysis package.
452-457

- Jochen Hampe, T. Wienker, Stefan Schreiber, P. Nurnberg:
POPSIM: a general population simulation program.
458-464

- P. Lindenbaum:
CloneIt: finding cloning strategies, in-frame deletions and frameshifts.
465-466

- V. Proutski, E. Holmes:
SWAN: sliding window analysis of nucleotide sequence variability.
467-468

- Patricia Rodriguez-Tomé:
The BioCatalog.
469-470

Volume 14, Number 6, July 1998
Articles
- Toshitsugu Okayama, Takuro Tamura, Takashi Gojobori, Yoshio Tateno, Kazuho Ikeo, Satoru Miyazaki, Kaoru Fukami-Kobayashi, Hideaki Sugawara:
Formal design and implementation of an improved DDBJ DNA database with a new schema and object-oriented library.
472-478

- S. Z. Maltchenko:
The bio-objects project. Part I: the object data model core elements.
479-485

- Kei-Hoi Cheung, Prakash M. Nadkarni, Dong-Guk Shin:
A metadata approach to query interoperation between molecular biology databases.
486-497

- Eivind Coward, Finn Drabløs:
Detecting periodic patterns in biological sequences.
498-507

- Pierre Nicodème:
SSMAL: similarity searching with alignment graphs.
508-515

- Xavier Pennec, Nicholas Ayache:
A geometric algorithm to find small but highly similar 3D substructures in proteins.
516-522

- R. Rodriguez, G. Chinea, N. Lopez, T. Pons, Gert Vriend:
Homology modeling, model and software evaluation: three related resources.
523-528

- F. A. Kolpakov, Elena A. Ananko, G. B. Kolesov, Nikolay A. Kolchanov:
GeneNet: a gene network database and its automated visualization.
529-537

- Carol Soderlund, Timun Lau, Panos Deloukas:
Z extensions to the RHMAPPER package.
538-539

- Foo-Tim Chau, Tsz-Pun Chan, Jing Wang:
TLCQA: quantitative study of thin-layer chromatography.
540-541

- Javier Tamames, Christos A. Ouzounis, Georg Casari, Chris Sander, Alfonso Valencia:
EUCLID: automatic classification of proteins in functional classes by their database annotations.
542-543

- Oswaldo Trelles, C. Ceron, Huaichun Wang, Joaquín Dopazo, José María Carazo:
New phylogenetic venues opened by a novel implementation of the DNAml algorithm.
544-545

- V. N. Serov, Alexander V. Spirov, Maria Samsonova:
Graphical interface to the genetic network database GeNet.
546-547

Volume 14, Number 7, August 1998
Editorials
- Russ B. Altman:
A curriculum for bioinformatics: the time is ripe.
549-550

Articles
- Dmitrij Frishman, Klaus Heumann, A. Lesk, Hans-Werner Mewes:
Comprehensive, comprehensible, distributed and intelligent databases: current status.
551-561

- Nathan Goodman, Steve Rozen, Lincoln Stein, A. G. Smith:
The LabBase system for data management in large scale biology research laboratories.
562-574

- John Macauley, Huajun Wang, Nathan Goodman:
A model system for studying the integration of molecular biology databases.
575-582

- Ulf Leser, Hans Lehrach, Hugues Roest Crollius:
Issues in developing integrated genomic databases and application to the human X chromosome.
583-590

- Susumu Goto, Takaaki Nishioka, Minoru Kanehisa:
LIGAND: chemical database for enzyme reactions.
591-599

- Miguel A. Andrade, Alfonso Valencia:
Automatic extraction of keywords from scientific text: application to the knowledge domain of protein families.
600-607

- P. H. Sneath:
The effect of evenly spaced constant sites on the distribution of the random division of a molecular sequence.
608-616

- Kenji Mizuguchi, Charlotte M. Deane, Tom L. Blundell, Mark S. Johnson, John P. Overington:
JOY: protein sequence-structure representation and analysis.
617-623

- Therese E. Malliavin, Jean-Luc Pons, Marc-André Delsuc:
An NMR assignment module implemented in the Gifa NMR processing program.
624-631

- Dean W. Podlich, Mark Cooper:
QU-GENE: a simulation platform for quantitative analysis of genetic models.
632-653

Volume 14, Number 8, September 1998
Articles
- Michael Rebhan, Vered Chalifa-Caspi, J. Prilusky, Doron Lancet:
GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support.
656-664

- K. Murakami, T. Takagi:
Gene recognition by combination of several gene-finding programs.
665-675

- Salvatore Rampone:
Recognition of splice junctions on DNA sequences by BRAIN learning algorithm.
676-684

- M. Yan, Z. S. Lin, C. T. Zhang:
A new fourier transform approach for protein coding measure based on the format of the Z curve.
685-690

- Jack E. Tabaska, Robert B. Cary, Harold N. Gabow, Gary D. Stormo:
An RNA folding method capable of identifying pseudoknots and base triples.
691-699

- Li Wuju, W. JiaJin:
Prediction of RNA secondary structure based on helical regions distribution.
700-706

- Mark Gerstein:
Measurement of the effectiveness of transitive sequence comparison, through a third 'intermediate' sequence.
707-714

- Pierre Vincens, L. Buffat, Cécile André, Jean-Paul Chevrolat, Jean-François Boisvieux, Serge A. Hazout:
A strategy for finding regions of similarity in complete genome sequences.
715-725

- Pietro Liò, N. Goldman, Jeffrey L. Thorne, David T. Jones:
PASSML: combining evolutionary inference and protein secondary structure prediction.
726-733

- Kim Jungfer, Patricia Rodriguez-Tomé:
Mapplet: a CORBA-based genome map viewer.
734-738

- J. Boyle:
A visual environment for the manipulation and integration of JAVA beans.
739-748

- C. M. Pasquier, Vassilis J. Promponas, N. J. Varvayannis, Stavros J. Hamodrakas:
A web server to locate periodicities in a sequence.
749-750

- T. R. Burglin:
PPCMatrix: a PowerPC dotmatrix program to compare large genomic sequences against protein sequences.
751-752

Volume 14, Number 9, October 1998
Articles:
- Sean R. Eddy:
Profile hidden Markov models.
755-763

- Eileen Kraemer, Thomas E. Ferrin:
Molecules to maps: tools for visualization and interaction in support of computational biology.
764-771

- Rachel Karchin, Richard Hughey:
Weighting hidden Markov models for maximum discrimination.
772-782

- X. Guan, L. Du:
Domain identification by clustering sequence alignments.
783-788

- Katsuhisa Horimoto, M. Suyama, Hiroyuki Toh, Kentaro Mori, Jinya Otsuka:
A method for comparing circular genomes from gene locations: application to mitochondrial genomes.
789-802

- L. B. Ellis, S. M. Speedie, R. McLeish:
Representing metabolic pathway information: an object-oriented approach.
803-806

- Stuart Pook, Guy Vaysseix, Emmanuel Barillot:
Zomit: biological data visualization and browsing.
807-814

- Giovanni Iazzetti, G. Santini, M. Rau, E. Bucci, Raffaele Calogero:
VIRTLAB: a virtual molecular biology laboratory.
815-816

- David Posada, Keith A. Crandall:
MODELTEST: testing the model of DNA substitution.
817-818

- Roderic D. M. Page:
GeneTree: comparing gene and species phylogenies using reconciled trees.
819-820

- Mark R. Southern, A. P. Lewis:
JavaShade: multiple sequence alignment box-and-shading on the World Wide Web.
821-822

- Matthew R. Pocock, Tim J. P. Hubbard, Ewan Birney:
SPEM: a parser for EMBL style flat file database entries.
823-824

- W. Newell, P. Sanseau, J. Riley, A. Lyall:
WEBMAP: radiation hybrid mapping on the WWW.
825-826

- Matthias Wjst, Thomas Immervoll:
An Internet linkage and mutation database for the complex phenotype asthma.
827-828

Volume 14, Number 10, November 1998
Articles
- Emmet A. O'Brien, Desmond G. Higgins:
Empirical estimation of the reliability of ribosomal RNA alignments.
830-838

- Torbjørn Rognes, Erling Seeberg:
SALSA: improved protein database searching by a new algorithm for assembly of sequence fragments into gapped alignments.
839-845

- Kevin Karplus, Christian Barrett, Richard Hughey:
Hidden Markov models for detecting remote protein homologies.
846-856

- C. T. Zhang, R. Zhang:
A new criterion to classify globular proteins based on their secondary structure contents.
857-865

- W. J. Lin, M. J. Hwang:
VHMPT: a graphical viewer and editor for helical membrane protein topologies.
866-868

- Pedro Mendes, Douglas B. Kell:
Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation.
869-883

- L. W. Ju, L. H. Xing, P. W. Hong, W. J. Jin:
GeneDn: for high-level expression design of heterologous genes in a prokaryotic system.
884-885

- C. P. Goujon, V. M. Schneider, C. Jacomet, J. C. Nicolas:
HIV-1 genotypic resistance: automated sequence analysis and interpretation.
886-887

- M. Rimer, Michael O'Connell:
BioABACUS: a database of abbreviations and acronyms in biotechnology and computer science.
888-889

- K. C. Worley, P. Culpepper, B. A. Wiese, R. F. Smith:
BEAUTY-X: enhanced BLAST searches for DNA queries.
890-891

- James A. Cuff, Michele E. Clamp, Asim S. Siddiqui, M. Finlay, Geoffrey J. Barton:
JPred: a consensus secondary structure prediction server.
892-893

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