Volume 41, Number 1, February 2008

• 
  Jau-Huei Lin, Peter J. Haug: Exploiting missing clinical data in Bayesian network modeling for predicting medical problems. 1-14
• 
  Fatma Latifoglu, Kemal Polat, Sadik Kara, Salih Günes: Medical diagnosis of atherosclerosis from Carotid Artery Doppler Signals using principal component analysis (PCA), k-NN based weighting pre-processing and Artificial Immune Recognition System (AIRS). 15-23
• 
  Paolo Contiero, Andrea Tittarelli, Anna Maghini, Sabrina Fabiano, Emanuela Frassoldi, Enrica Costa, Daniela Gada, Tiziana Codazzi, Paolo Crosignani, Roberto Tessandori, Giovanna Tagliabue: Comparison with manual registration reveals satisfactory completeness and efficiency of a computerized cancer registration system. 24-32
• 
  Joan Valls, Mònica Grau, Xavier Solé, Pilar Hernández, David Montaner, Joaquín Dopazo, Miguel A. Peinado, Gabriel Capellá, Víctor Moreno, Miguel Angel Pujana: CLEAR-test: Combining inference for differential expression and variability in microarray data analysis. 33-45
• 
  Guy Tsafnat: The Field Representation Language. 46-57
• 
  Mark Elliot, Kingsley Purdam, Duncan Smith: Statistical disclosure control architectures for patient records in biomedical information systems. 58-64
• 
  Razib M. Othman, Safaai Deris, Rosli Md. Illias: A genetic similarity algorithm for searching the Gene Ontology terms and annotating anonymous protein sequences. 65-81
• 
  Magnus Irestig, Toomas Timpka: Politics and technology in health information systems development: A discourse analysis of conflicts addressed in a systems design group. 82-94
• 
  Hau-San Wong, Hong-Qiang Wang: Constructing the gene regulation-level representation of microarray data for cancer classification. 95-105
• 
  George A. Komatsoulis, Denise B. Warzel, Francis W. Hartel, Krishnakant Shanbhag, Ram Chilukuri, Gilberto Fragoso, Sherri de Coronado, Dianne M. Reeves, Jillaine B. Hadfield, Christophe Ludet, Peter A. Covitz: caCORE version 3: Implementation of a model driven, service-oriented architecture for semantic interoperability. 106-123
• 
  Hyunjin Shin, Bryan Sheu, Maria Joseph, Mia K. Markey: Guilt-by-association feature selection: Identifying biomarkers from proteomic profiles. 124-136
• 
  A. Narasimhadevara, Thiruvengadam Radhakrishnan, B. Leung, R. Jayakumar: On designing a usable interactive system to support transplant nursing. 137-151
• 
  Nathan C. Hulse, Guilherme Del Fiol, Richard L. Bradshaw, Lorrie K. Roemer, Roberto A. Rocha: Towards an on-demand peer feedback system for a clinical knowledge base: A case study with order sets. 152-164
• 
  Themis P. Exarchos, Costas Papaloukas, Christos Lampros, Dimitrios I. Fotiadis: Mining sequential patterns for protein fold recognition. 165-179
• 
  Mor Peleg, Sagi Keren, Yaron Denekamp: Mapping computerized clinical guidelines to electronic medical records: Knowledge-data ontological mapper (KDOM). 180-201
• 
  Theodosios Theodosiou, Lefteris Angelis, Athena Vakali: Non-linear correlation of content and metadata information extracted from biomedical article datasets. 202-216

Volume 41, Number 2, April 2008

• 
  Lefteris Gortzis, George Nikiforidis: Tracing and cataloguing knowledge in an e-health cardiology environment. 217-223
• 
  Yanna Shen, Christina Adamou, John N. Dowling, Gregory F. Cooper: Estimating the joint disease outbreak-detection time when an automated biosurveillance system is augmenting traditional clinical case finding. 224-231
• 
  Jihun Kim, Hee-Joon Chung, Yong Jung, Kack-Kyun Kim, Ju Han Kim: BioLattice: A framework for the biological interpretation of microarray gene expression data using concept lattice analysis. 232-241
• 
  Susan Maskery, Hai Hu, Jeffrey Hooke, Craig D. Shriver, Michael N. Liebman: A Bayesian derived network of breast pathology co-occurrence. 242-250
• 
  Ion-Florin Talos, Daniel L. Rubin, Michael Halle, Mark A. Musen, Ron Kikinis: A prototype symbolic model of canonical functional neuroanatomy of the motor system. 251-263
• 
  Xingwei Wang, Shibo Li, Hong Liu, Marc C. Wood, Wei R. Chen, Bin Zheng: Automated identification of analyzable metaphase chromosomes depicted on microscopic digital images. 264-271
• 
  Bo Geng, Xiaobo Zhou, Jinmin Zhu, Y. S. Hung, Stephen T. C. Wong: Comparison of reversible-jump Markov-chain-Monte-Carlo learning approach with other methods for missing enzyme identification. 272-281
• 
  Waclaw Kusnierczyk: Taxonomy-based partitioning of the Gene Ontology. 282-292
• 
  Yan Chen, Yehoshua Perl, James Geller, George Hripcsak, Li Zhang: Comparing and consolidating two heuristic metaschemas. 293-317
• 
  Siriwan Suebnukarn, Peter Haddawy, Phattanapon Rhienmora: A collaborative medical case authoring environment based on the UMLS. 318-326
• 
  Sofie Pilemalm, Toomas Timpka: Third generation participatory design in health informatics - Making user participation applicable to large-scale information system projects. 327-339
• 
  Hsin-Min Lu, Daniel Zeng, Lea Trujillo, Ken Komatsu, Hsinchun Chen: Ontology-enhanced automatic chief complaint classification for syndromic surveillance. 340-356
• 
  Peter W. Hung, Stephen B. Johnson, David R. Kaufman, Eneida A. Mendonça: A multi-level model of information seeking in the clinical domain. 357-370
• 
  Chih-Lin Chi, W. Nick Street, Marcia M. Ward: Building a hospital referral expert system with a Prediction and Optimization-Based Decision Support System algorithm. 371-386
• 
  Dean F. Sittig, Adam Wright, Jerome A. Osheroff, Blackford Middleton, Jonathan M. Teich, Joan S. Ash, Emily M. Campbell, David W. Bates: Grand challenges in clinical decision support. 387-392

Methodological Review

• 
  Deyu Zhou, Yulan He: Extracting interactions between proteins from the literature. 393-407

Volume 41, Number 3, June 2008

Computerized Decision Support for Critical and Emergency Care

• 
  Tze-Yun Leong, Dominik Aronsky, M. Michael Shabot: Computer-based decision support for critical and emergency care. 409-412

Methodological Reviews

• 
  Vimla L. Patel, Jiajie Zhang, Nicole A. Yoskowitz, Robert A. Green, Osman R. Sayan: Translational cognition for decision support in critical care environments: A review. 413-431
• 
  María M. Abad-Grau, Jorge Ierache, Claudio Cervino, Paola Sebastiani: Evolution and challenges in the design of computational systems for triage assistance. 432-441

Research Papers

• 
  Anton Aboukhalil, Larry Nielsen, Mohammed Saeed, Roger G. Mark, Gari D. Clifford: Reducing false alarm rates for critical arrhythmias using the arterial blood pressure waveform. 442-451
• 
  Ying Zhang, Peter Szolovits: Patient-specific learning in real time for adaptive monitoring in critical care. 452-460
• 
  D. Sorenson, C. K. Grissom, L. Carpenter, A. Austin, Katherine A. Sward, L. Napoli, Homer R. Warner, Alan H. Morris: A frame-based representation for a bedside ventilator weaning protocol. 461-468
• 
  Liangyou Chen, Thomas M. McKenna, Andrew T. Reisner, Andrei V. Gribok, Jaques Reifman: Decision tool for the early diagnosis of trauma patient hypovolemia. 469-478
• 
  Madhu C. Reddy, M. Michael Shabot, Erin Bradner: Evaluating collaborative features of critical care systems: A methodological study of information technology in surgical intensive care units. 479-487
• 
  Katherine A. Sward, J. Orme Jr., D. Sorenson, L. Baumann, Alan H. Morris: Reasons for declining computerized insulin protocol recommendations: Application of a framework. 488-497

Volume 41, Number 4, August 2008

• 
  Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence S. Dooley, Ross L. Coppel: Ameliorative missing value imputation for robust biological knowledge inference. 499-514
• 
  Marcel van Gerven, Babs G. Taal, Peter J. F. Lucas: Dynamic Bayesian networks as prognostic models for clinical patient management. 515-529
• 
  Xiaogang Ruan, Jinlian Wang, Hui Li, Rhoda E. Perozzi, Edmund F. Perozzi: The use of logic relationships to model colon cancer gene expression networks with mRNA microarray data. 530-543
• 
  Paola Berchialla, A. Stancu, Cecilia Scarinzi, Silvia Snidero, R. Corradetti, Dario Gregori: Web-based tool for injury risk assessment of foreign body injuries in children. 544-556
• 
  Isabella Scandurra, Maria Hägglund, Sabine Koch: From user needs to system specifications: Multi-disciplinary thematic seminars as a collaborative design method for development of health information systems. 557-569
• 
  Hsi-Che Liu, Chien-Yu Chen, Yu-Ting Liu, Cheng-Bang Chu, Der-Cherng Liang, Lee-Yung Shih, Chih-Jen Lin: Cross-generation and cross-laboratory predictions of Affymetrix microarrays by rank-based methods. 570-579
• 
  Zhihao Yang, Hongfei Lin, Yanpeng Li: Exploiting the contextual cues for bio-entity name recognition in biomedical literature. 580-587
• 
  Igor Trajkovski, Nada Lavrac, Jakub Tolar: SEGS: Search for enriched gene sets in microarray data. 588-601
• 
  Weixiang Liu, Kehong Yuan, Datian Ye: Reducing microarray data via nonnegative matrix factorization for visualization and clustering analysis. 602-606
• 
  C. George Priya Doss, C. Sudandiradoss, R. Rajasekaran, Rituraj Purohit, K. Ramanathan, Rao Sethumadhavan: Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: A bio-informatics study. 607-612
• 
  Jagan Dara, John N. Dowling, Debbie Travers, Gregory F. Cooper, Wendy Webber Chapman: Evaluation of preprocessing techniques for chief complaint classification. 613-623
• 
  Cornelia M. Ruland, Justin Starren, Torun M. Vatne: Participatory design with children in the development of a support system for patient-centered care in pediatric oncology. 624-635
• 
  Ben Medlock: Exploring hedge identification in biomedical literature. 636-654
• 
  Guilherme Del Fiol, Peter J. Haug: Infobuttons and classification models: A method for the automatic selection of on-line information resources to fulfill clinicians' information needs. 655-666
• 
  Vladimir Brtka, Edith Stokic, Biljana Srdic: Automated extraction of decision rules for leptin dynamics - A rough sets approach. 667-674
• 
  Aykut M. Uslu, Jürgen Stausberg: Value of the electronic patient record: An analysis of the literature. 675-682

Volume 41, Number 5, October 2008

• 
  Kei-Hoi Cheung, Vipul Kashyap, Joanne Luciano, Huajun Chen, Yimin Wang, Susie Stephens: Semantic mashup of biomedical data. 683-686
• 
  Carole A. Goble, Robert Stevens: State of the nation in data integration for bioinformatics. 687-693
• 
  Kei-Hoi Cheung, Kevin Y. Yip, Jeffrey P. Townsend, Matthew Scotch: HCLS 2.0/3.0: Health care and life sciences data mashup using Web 2.0/3.0. 694-705
• 
  François Belleau, Marc-Alexandre Nolin, Nicole Tourigny, Philippe Rigault, Jean Morissette: Bio2RDF: Towards a mashup to build bioinformatics knowledge systems. 706-716
• 
  Ranga Chandra Gudivada, Xiaoyan A. Qu, Jing Chen, Anil G. Jegga, Eric K. Neumann, Bruce J. Aronow: Identifying disease-causal genes using Semantic Web-based representation of integrated genomic and phenomic knowledge. 717-729
• 
  Sapna Bafna, Julian Humphries, Daniel P. Miranker: Schema driven assignment and implementation of life science identifiers (LSIDs). 730-738
• 
  Paolo Ciccarese, Elizabeth Wu, Gwendolyn T. Wong, Marco Ocana, June Kinoshita, Alan Ruttenberg, Tim Clark: The SWAN biomedical discourse ontology. 739-751
• 
  Satya Sanket Sahoo, Olivier Bodenreider, Joni L. Rutter, Karen J. Skinner, Amit P. Sheth: An ontology-driven semantic mashup of gene and biological pathway information: Application to the domain of nicotine dependence. 752-765
• 
  Lynda Temal, Michel Dojat, Gilles Kassel, Bernard Gibaud: Towards an ontology for sharing medical images and regions of interest in neuroimaging. 766-778
• 
  Natalia Villanueva-Rosales, Michel Dumontier: yOWL: An ontology-driven knowledge base for yeast biologists. 779-789
• 
  Yuxin Mao, Zhaohui Wu, Wenya Tian, Xiaohong Jiang, William K. Cheung: Dynamic sub-ontology evolution for traditional Chinese medicine web ontology. 790-805
• 
  Menaka Rajapakse, Kanagasabai Rajaraman, Wee Tiong Ang, Anitha Veeramani, Mark J. Schreiber, Christopher J. O. Baker: Ontology-centric integration and navigation of the dengue literature. 806-815
• 
  Vít Novácek, Loredana Laera, Siegfried Handschuh, Brian Davis: Infrastructure for dynamic knowledge integration - Automated biomedical ontology extension using textual resources. 816-828
• 
  Jiangbo Dang, Amir Hedayati, Ken Hampel, Candemir Toklu: An ontological knowledge framework for adaptive medical workflow. 829-836
• 
  Michael DiBernardo, Rachel Pottinger, Mark Wilkinson: Semi-automatic web service composition for the life sciences using the BioMoby semantic web framework. 837-847
• 
  Francisco García Sánchez, Jesualdo Tomás Fernández-Breis, Rafael Valencia-García, Juan Miguel Gómez, Rodrigo Martínez-Béjar: Combining Semantic Web technologies with Multi-Agent Systems for integrated access to biological resources. 848-859

Volume 41, Number 6, December 2008

• 
  Kishore Mosaliganti, Tony Pan, Randall Ridgway, Richard Sharp, Lee A. D. Cooper, Alex Gulacy, Ashish Sharma, M. Okan Irfanoglu, Raghu Machiraju, Tahsin M. Kurç, Alain de Bruin, Pamela Wenzel, Gustavo Leone, Joel H. Saltz, Kun Huang: An imaging workflow for characterizing phenotypical change in large histological mouse model datasets. 863-873
• 
  Mehmet Korürek, Ali Nizam: A new arrhythmia clustering technique based on Ant Colony Optimization. 874-881
• 
  Hui Cao, Genevieve B. Melton, Marianthi Markatou, George Hripcsak: Use abstracted patient-specific features to assist an information-theoretic measurement to assess similarity between medical cases. 882-888
• 
  Erez Shalom, Yuval Shahar, Meirav Taieb-Maimon, Guy Bar, Avi Yarkoni, Ohad Young, Susana B. Martins, Laszlo T. Vaszar, Mary K. Goldstein, Yair Liel, Akiva Leibowitz, Tal Marom, Eitan Lunenfeld: A quantitative assessment of a methodology for collaborative specification and evaluation of clinical guidelines. 889-903
• 
  Barry Cohen, Marc Oren, Hua Min, Yehoshua Perl, Michael Halper: Automated comparative auditing of NCIT genomic roles using NCBI. 904-913
• 
  Emma Steele, Allan Tucker: Consensus and Meta-analysis regulatory networks for combining multiple microarray gene expression datasets. 914-926
• 
  Jonathan C. Silverstein, Nigel M. Parsad, Victor Tsirline: Automatic perceptual color map generation for realistic volume visualization. 927-935
• 
  Nenad S. Mitic, Gordana Pavlovic-Lazetic, Milos V. Beljanski: Could n-gram analysis contribute to genomic island determination? 936-943
• 
  Ray S. Lin, Susan D. Horn, John F. Hurdle, Alexander S. Goldfarb-Rumyantzev: Single and multiple time-point prediction models in kidney transplant outcomes. 944-952
• 
  Yao-Ting Huang, Kun-Mao Chao: A new framework for the selection of tag SNPs by multimarker haplotypes. 953-961
• 
  Adam Wright, Dean F. Sittig: SANDS: A service-oriented architecture for clinical decision support in a National Health Information Network. 962-981
• 
  Adam Wright, Dean F. Sittig: A framework and model for evaluating clinical decision support architectures. 982-990
• 
  Richard Moreau, V. Ochoa, Minh Tu Pham, Pierre Boulanger, Tanneguy Redarce, Olivier Dupuis: A method to evaluate skill transfer and acquisition of obstetric gestures based on the curvatures analysis of the position and the orientation. 991-1000
• 
  Eric S. Hall, Mollie R. Poynton, Scott P. Narus, Sidney N. Thornton: Modeling the distribution of Nursing Effort using structured Labor and Delivery documentation. 1001-1008
• 
  Brian C. Drolet, Kevin B. Johnson: Categorizing the world of registries. 1009-1020
• 
  Tai-Been Chen, Henry Horng-Shing Lu, Yun-Shien Lee, Hsiu-Jen Lan: Segmentation of cDNA microarray images by kernel density estimation. 1021-1027
• 
  Mor Peleg, Dizza Beimel, Dov Dori, Yaron Denekamp: Situation-Based Access Control: Privacy management via modeling of patient data access scenarios. 1028-1040
• 
  Christa E. Bartos, Douglas B. Fridsma, Brian S. Butler, Louis E. Penrod, Michael J. Becich, Rebecca S. Crowley: Development of an instrument for measuring clinicians' power perceptions in the workplace. 1041-1049
• 
  Murat Cokol, Raul Rodriguez-Esteban: Visualizing evolution and impact of biomedical fields. 1050-1052
• 
  Ismail Abbas, Joan Rovira, Josep Casanovas, Tony Greenfield: Optimal design of clinical trials with computer simulation based on results of earlier trials, illustrated with a lipodystrophy trial in HIV patients. 1053-1061
• 
  James E. Andrews, Timothy B. Patrick, Rachel L. Richesson, Hana Brown, Jeffrey P. Krischer: Comparing heterogeneous SNOMED CT coding of clinical research concepts by examining normalized expressions. 1062-1069
• 
  Trevor Cohen, Brett Blatter, Vimla L. Patel: Simulating expert clinical comprehension: Adapting latent semantic analysis to accurately extract clinical concepts from psychiatric narrative. 1070-1087
• 
  Guergana K. Savova, Anni Coden, Igor L. Sominsky, Rie Johnson, Philip V. Ogren, Piet C. de Groen, Christopher G. Chute: Word sense disambiguation across two domains: Biomedical literature and clinical notes. 1088-1100