Isaac S. Kohane

Isaac S. Kohane, Vladimir I. Valtchinov: Quantifying the white blood cell transcriptome as an accessible window to the multiorgan transcriptome. Bioinformatics 28(4): 538-545 (2012)

Isaac S. Kohane, Vladimir I. Valtchinov: Quantifying the white blood cell transcriptome as an accessible window to the multiorgan transcriptome. Bioinformatics 28(6): 905 (2012)

Isaac S. Kohane, Susanne Churchill, Shawn N. Murphy: A translational engine at the national scale: informatics for integrating biology and the bedside. JAMIA 19(2): 181-185 (2012)

Kenneth D. Mandl, Joshua C. Mandel, Shawn N. Murphy, Elmer V. Bernstam, Rachel L. Ramoni, David A. Kreda, J. Michael McCoy, Ben Adida, Isaac S. Kohane: The SMART Platform: early experience enabling substitutable applications for electronic health records. JAMIA 19(4): 597-603 (2012)

Daniel R. Masys, Gail P. Jarvik, Neil F. Abernethy, Nicholas R. Anderson, George J. Papanicolaou, Dina N. Paltoo, Mark A. Hoffman, Isaac S. Kohane, Howard P. Levy: Technical desiderata for the integration of genomic data into Electronic Health Records. Journal of Biomedical Informatics 45(3): 419-422 (2012)

Mark Y. Tong, Christopher A. Cassa, Isaac S. Kohane: Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations. Bioinformatics 27(6): 891-893 (2011)

Shashank Agarwal, Hong Yu, Isaac S. Kohane: BioNOT: A searchable database of biomedical negated sentences. BMC Bioinformatics 12: 420 (2011)

Isaac S. Kohane, Peter Szolovits: Marco Ramoni: an appreciation of academic achievement. JAMIA 18(4): 367-369 (2011)

Shawn N. Murphy, Vivian Gainer, Michael Mendis, Susanne Churchill, Isaac S. Kohane: Strategies for maintaining patient privacy in i2b2. JAMIA 18(Supplement): 103-108 (2011)

Fulvia Ferrazzi, Felix B. Engel, Erxi Wu, Annie P. Moseman, Isaac S. Kohane, Riccardo Bellazzi, Marco Ramoni: Inferring cell cycle feedback regulation from gene expression data. Journal of Biomedical Informatics 44(4): 565-575 (2011)

Susan L. Graham, Deborah Estrin, Eric Horvitz, Isaac S. Kohane, Elizabeth D. Mynatt, Ida Sim: Information Technology research challenges for healthcare: from discovery to delivery. SIGHIT Record 1(1): 4-9 (2011)

Shawn N. Murphy, Griffin M. Weber, Michael Mendis, Vivian Gainer, Henry C. Chueh, Susanne Churchill, Isaac S. Kohane: Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). JAMIA 17(2): 124-130 (2010)

Peter J. Park, Sek Won Kong, Toma Tebaldi, Weil R. Lai, Simon Kasif, Isaac S. Kohane: Integration of heterogeneous expression data sets extends the role of the retinol pathway in diabetes and insulin resistance. Bioinformatics 25(23): 3121-3127 (2009)

Blanca E. Himes, Yi Dai, Isaac S. Kohane, Scott T. Weiss, Marco Ramoni: Research Paper: Prediction of Chronic Obstructive Pulmonary Disease (COPD) in Asthma Patients Using Electronic Medical Records. JAMIA 16(3): 371-379 (2009)

Griffin M. Weber, Shawn N. Murphy, Andrew J. McMurry, Douglas MacFadden, Daniel J. Nigrin, Susanne Churchill, Isaac S. Kohane: Application of Information Technology: The Shared Health Research Information Network (SHRINE): A Prototype Federated Query Tool for Clinical Data Repositories. JAMIA 16(5): 624-630 (2009)

m. c. schraefel, Paul André, Ryen White, Desney S. Tan, Tim Berners-Lee, Sunny Consolvo, Robert Jacobs, Isaac S. Kohane, Christopher A. Le Dantec, Lena Mamykina, Gary Marsden, Ben Shneiderman, Peter Szolovits, Daniel J. Weitzner: Interacting with eHealth: towards grand challenges for HCI. CHI Extended Abstracts 2009: 3309-3312

Özlem Uzuner, Ira Goldstein, Yuan Luo, Isaac S. Kohane: Viewpoint Paper: Identifying Patient Smoking Status from Medical Discharge Records. JAMIA 15(1): 14-24 (2008)

Isaac S. Kohane, Özlem Uzuner: Letters to the Editor: No Structure Before Its Time. JAMIA 15(5): 708 (2008)

Andrew J. McMurry, Clint A. Gilbert, Ben Y. Reis, Henry C. Chueh, Isaac S. Kohane, Kenneth D. Mandl: Model Formulation: A Self-scaling, Distributed Information Architecture for Public Health, Research, and Clinical Care. JAMIA 14(4): 527-533 (2007)

Voichita D. Marinescu, Isaac S. Kohane, Tae-Kyung Kim, David A. Harmin, Michael E. Greenberg, Alberto Riva: START: an automated tool for serial analysis of chromatin occupancy data. Bioinformatics 22(8): 999-1001 (2006)

Hidenori Inaoka, Yutaka Fukuoka, Isaac S. Kohane: Lower expression of genes near microRNA in C. elegans germline. BMC Bioinformatics 7: 112 (2006)

Fulvia Ferrazzi, Paola Sebastiani, Isaac S. Kohane, Marco Ramoni, Riccardo Bellazzi: Dynamic Bayesian Networks in Modelling Cellular Systems: a Critical Appraisal on Simulated Data. CBMS 2006: 544-549

Sek Won Kong, Kyu Baek Hwang, Richard D. Kim, Byoung-Tak Zhang, Steven A. Greenberg, Isaac S. Kohane, Peter J. Park: CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays. Bioinformatics 21(9): 2116-2117 (2005)

Voichita D. Marinescu, Isaac S. Kohane, Alberto Riva: MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes. BMC Bioinformatics 6: 79 (2005)

Scott L. Carter, Aron C. Eklund, Brigham H. Mecham, Isaac S. Kohane, Zoltan Szallasi: Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements. BMC Bioinformatics 6: 107 (2005)

Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte: Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks. BMC Bioinformatics 6: 227 (2005)

William W. Simons, Kenneth D. Mandl, Isaac S. Kohane: Model Formulation: The PING Personally Controlled Electronic Medical Record System: Technical Architecture. JAMIA 12(1): 47-54 (2005)

Ulrich Sax, Isaac S. Kohane, Kenneth D. Mandl: Position Paper: Wireless Technology Infrastructures for Authentication of Patients: PKI that Rings. JAMIA 12(3): 263-268 (2005)

Stephen C. Porter, Isaac S. Kohane, Donald A. Goldmann: Research Paper: Parents as Partners in Obtaining the Medication History. JAMIA 12(3): 299-305 (2005)

Voichita D. Marinescu, Isaac S. Kohane, Alberto Riva: The MAPPER database: a multi-genome catalog of putative transcription factor binding sites. Nucleic Acids Research 33(Database-Issue): 91-97 (2005)

Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte: Quantifying the relationship between co-expression, co-regulation and gene function. BMC Bioinformatics 5: 18 (2004)

Alberto Riva, Isaac S. Kohane: A SNP-centric database for the investigation of the human genome. BMC Bioinformatics 5: 33 (2004)

Charles P. Friedman, Russ B. Altman, Isaac S. Kohane, Kathleen A. McCormick, Perry L. Miller, Judy G. Ozbolt, Edward H. Shortliffe, Gary D. Stormo, M. Cleat Szczepaniak, David Tuck, Jeffrey J. Williamson: White Paper: Training the Next Generation of Informaticians: The Impact of "BISTI" and Bioinformatics - A Report from the American College of Medical Informatics. JAMIA 11(3): 167-172 (2004)

Stephen C. Porter, Zhaohui Cai, William Gribbons, Donald A. Goldmann, Isaac S. Kohane: Application of Information Technology: The Asthma Kiosk: A Patient-centered Technology for Collaborative Decision Support in the Emergency Department. JAMIA 11(6): 458-467 (2004)

Kyungjoon Lee, Isaac S. Kohane, Atul J. Butte: PGAGENE: integrating quantitative gene-specific results from the NHLBI Programs for Genomic Applications. Bioinformatics 19(6): 778-779 (2003)

Ashish Nimgaonkar, Despina Sanoudou, Atul J. Butte, Judith N. Haslett, Louis M. Kunkel, Alan H. Beggs, Isaac S. Kohane: Reproducibility of gene expression across generations of Affymetrix microarrays. BMC Bioinformatics 4: 27 (2003)

Paola Sebastiani, Isaac S. Kohane, Marco Ramoni: Editorial: Methods in Functional Genomics. Machine Learning 52(1-2): 5-9 (2003)

Francisco M. de la Vega, Kenneth K. Kidd, Isaac S. Kohane: Human Genome Variation: Haplotypes, Linkage Disequilibrium, and Populations - Session Introduction. Pacific Symposium on Biocomputing 2003: 463-465

Winston Patrick Kuo, Tor-Kristian Jenssen, Atul J. Butte, Lucila Ohno-Machado, Isaac S. Kohane: Analysis of matched mRNA measurements from two different microarray technologies. Bioinformatics 18(3): 405-412 (2002)

Peter J. Park, Atul J. Butte, Isaac S. Kohane: Comparing expression profiles of genes with similar promoter regions. Bioinformatics 18(12): 1576-1584 (2002)

Alberto Riva, Isaac S. Kohane: SNPper: retrieval and analysis of human SNPs. Bioinformatics 18(12): 1681-1685 (2002)

Isaac S. Kohane: Brief Review: The Contributions of Biomedical Informatics to the Fight Against Bioterrorism. JAMIA 9(2): 116-119 (2002)

Ju-Han Kim, Isaac S. Kohane, Lucila Ohno-Machado: Visualization and evaluation of clusters for exploratory analysis of gene expression data. Journal of Biomedical Informatics 35(1): 25-36 (2002)

Peter J. Park, Lu Tian, Isaac S. Kohane: Linking gene expression data with patient survival times using partial least squares. ISMB 2002: 120-127

Francisco M. de la Vega, Isaac S. Kohane, J. A. Schneider, J. C. Stephens: Human Genome Variation: Disease, Drug Response, and Clinical Phenotypes - Session Introduction. Pacific Symposium on Biocomputing 2002: 3-5

Alberto Riva, Kenneth D. Mandl, Do Hoon Oh, Daniel J. Nigrin, Atul J. Butte, Peter Szolovits, Isaac S. Kohane: The Personal Internetworked Notary and Guardian. I. J. Medical Informatics 62(1): 27-40 (2001)

Ben Y. Reis, Atul J. Butte, Isaac S. Kohane: Extracting Knowledge from Dynamics in Gene Expression. Journal of Biomedical Informatics 34(1): 15-27 (2001)

Ben Y. Reis, Atul J. Butte, Isaac S. Kohane: Reply. Journal of Biomedical Informatics 34(4): 299-300 (2001)

Atul J. Butte, Ling Bao, Ben Y. Reis, Timothy W. Watkins, Isaac S. Kohane: Comparing the Similarity of Time-Series Gene Expression Using Signal Processing Metrics. Journal of Biomedical Informatics 34(6): 396-405 (2001)

Francisco M. de la Vega, Martin Kreitman, Isaac S. Kohane: Human Genome Variation: Linking Genotypes to Clinical Phenotypes - Session Introduction. Pacific Symposium on Biocomputing 2001: 3-5

Atul J. Butte, J. Ye, G. Niederfellner, K. Rett, H. U. Häring, M. F. White, Isaac S. Kohane: Determining Significant Fold Differences in Gene Expression Analysis. Pacific Symposium on Biocomputing 2001: 6-17

Ju-Han Kim, Lucila Ohno-Machado, Isaac S. Kohane: Unsupervised Learning from Complex Data: The Matrix Incision Tree Algorithm. Pacific Symposium on Biocomputing 2001: 30-41

Christine L. Tsien, T. A. Libermann, X. Gu, Isaac S. Kohane: On Reporting Fold Differences. Pacific Symposium on Biocomputing 2001: 496-507

Christine L. Tsien, Isaac S. Kohane, Neil McIntosh: Multiple signal integration by decision tree induction to detect artifacts in the neonatal intensive care unit. Artificial Intelligence in Medicine 19(3): 189-202 (2000)

Joseph Gonzalez-Heydrich, David Ray DeMaso, Connie Irwin, Ronald J. Steingard, Isaac S. Kohane, William R. Beardslee: Implementation of an electronic medical record system in a pediatric psychopharmacology program. I. J. Medical Informatics 57(2-3): 109-116 (2000)

Daniel J. Nigrin, Isaac S. Kohane: Application of Information Technology: Temporal Expressiveness in Querying a Time-stamp - based Clinical Database. JAMIA 7(2): 152-163 (2000)

Isaac S. Kohane: Bioinformatics and Clinical Informatics: The Imperative to Collaborate. JAMIA 7(5): 512-516 (2000)

Christine L. Tsien, Hamish S. F. Fraser, Isaac S. Kohane: LRTree: A Hybrid technique for Classifying Myocardial Infarction Data Containing Unknown Attribute Values. PAKDD 1998: 409-411

Ira J. Haimowitz, Isaac S. Kohane: Managing temporal worlds for medical trend diagnosis. Artificial Intelligence in Medicine 8(3): 299-321 (1996)

Isaac S. Kohane: Editorial. Artificial Intelligence in Medicine 7(6): 471-472 (1995)

Ira J. Haimowitz, P. P. Le, Isaac S. Kohane: Clinical monitoring using regression-based trend templates. Artificial Intelligence in Medicine 7(6): 473-496 (1995)

Ira J. Haimowitz, Isaac S. Kohane: An Epistemology for Clinically Significant Trends. AAAI 1993: 176-181

James C. Fackler, Isaac S. Kohane: Integration of intermittent clinical data with continuous data from bedside monitors. CBMS 1993: 289-294

Ira J. Haimowitz, Isaac S. Kohane: Automated Trend Detection with Alternate Temporal Hypotheses. IJCAI 1993: 146-151